SPECTRA Stats

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Lethal toxicity

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X-axis

Normalized Y-axis

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Points

Bars represent mean values with standard error (se), based on studies reporting lethal dose/concentration for 50% of the population (LC50/LD50)

Meta-analysis approach

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Risk ratios (RR) and confidence intervals (95% CI) derived from studies reporting lethal impact (mortality or survival rates in controlled trials). RR (95% CI) > 1 signifies high lethal risk, RR (95% CI) < 1 indicates low risk, and RR (95% CI) crossing x-axis at 1 implies no significant risk.

Meta-regression approach

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Prediction

Normalized quantity

Points

Prediction

Confidence interval

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Word trend

Total in database

Lethal toxicity

Meta-analysis approach

Meta-regression approach

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